- Dance Companies, Opelousas
- Day Spas, Opelousas
- Decorating & Designing Services, Opelousas
- Delicatessen Restaurants, Opelousas
- Dentists, Opelousas
- Deodorizing & Disinfecting Services, Opelousas
- Department Stores, Opelousas
- Dermatologists, Opelousas - Skin Doctors, Physicians & Surgeons (Dermatology)
- Designer Clothes & Accessories, Opelousas
- Diesel, Opelousas - Engine Fuels, Oils & Lubricants
- Diner Restaurants, Opelousas
- Direct Mail Advertising Services, Opelousas
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- Disability And Social Security Attorneys & Lawyers, Opelousas
- Discount Stores, Opelousas - Clothing, Grocery, Furniture, Etc
- Doctors, Physicians & Surgeons, Opelousas
- Dog & Horse Racing, Opelousas
- Donuts, Opelousas
- Doors & Door Frames, Opelousas - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drainage Contractors, Opelousas - Install & Repair Drainage Systems
- Drinking Establishments, Opelousas
- Drug Screening Services, Opelousas
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Opelousas
- Dry Cleaning & Laundry, Opelousas - Dry Cleaners
- Drywall, Insulation & Plaster Contractors, Opelousas - Installation & Repair Services
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