- Safety & Security Systems & Consultants, Donaldsonville
- Salvage Yards, Junk Yards & Wrecker Service, Donaldsonville
- Sand Gravel & Aggregate, Donaldsonville
- Sandwich Shop Restaurants, Donaldsonville
- Satellite Dish Antennas & Equipment Dealers, Donaldsonville
- Seafood Restaurants, Donaldsonville
- Secondary Schools, Donaldsonville
- Security & Surveillance System & Equipment, Donaldsonville
- Security Alarm Systems - Home & Business, Donaldsonville
- Security Brokers & Dealers, Donaldsonville
- Security Control Systems & Monitoring, Donaldsonville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Donaldsonville
- Senior Citizens Service & Health Organizations, Donaldsonville
- Sewer Construction Contractors, Donaldsonville - Sewer Line, Pipe Installation & Repair Services
- Sheriff's Department, Donaldsonville
- Shoe Stores, Donaldsonville - Mens, Womens & Kids Shoes
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- Shopping & Shopping Services, Donaldsonville
- Small Appliances, Donaldsonville
- Small Business & Office Equipment Repair Services, Donaldsonville
- Social Services & Welfare, Donaldsonville
- Sod & Sodding Service, Donaldsonville
- Space Planning, Donaldsonville
- Special Education & Care, Donaldsonville
- Specialty Stores, Donaldsonville
- Speech & Hearing Specialists, Donaldsonville
- Speech Pathologists, Donaldsonville - Speech & Language Therapy
- Sporting Goods Stores, Donaldsonville
- State Government, Donaldsonville
- Stock & Bond Brokers & Dealers, Donaldsonville
- Stocks & Bond Brokers, Donaldsonville
- Sugar Retail, Donaldsonville
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